There is a lot to be excited about on the Week 18 NFL schedule, including the Seattle Seahawks taking on the San Francisco 49ers. If you're seeking additional betting info for Week 18 in the NFL, we have you covered with odds for each of the important games.

After that, there are 14 more games coming up on Sunday. Check out our complete guide to NFL Week 18 below, including TV maps, announcers and kickoff times for each game. Carolina Panthers at Tampa Bay Buccaneers: Game starts at 4:30 p.m. ET on ESPN and ABC ( Announcers: Chris Fowler, Dan Orlovsky, Louis Riddick).

The Indianapolis Colts wrap up the 2025 NFL season on the road against the Houston Texans. The first time around, the Texans would win this matchup 20-16 in Indianapolis. So who do the NFL experts have winning this AFC South rematch?

Preview the Indianapolis Colts' NFL week 18 matchup with the Texans, including betting odds, tips, trends, and game information.